Sexual Health & NeuroendocrineIn StockSexual Health & Neuroendocrine
Kisspeptin-10
Also known as: Kp-10, Metastin(45-54)
C-terminal 10-amino-acid bioactive fragment of kisspeptin, used in neuroendocrine and reproductive-axis research.
Kisspeptin-10 (Kp-10) is the 10-amino-acid C-terminal active fragment of kisspeptin, a protein product of the KISS1 gene.
It is a potent agonist at the KISS1 receptor (KISS1R/GPR54), which plays a central role in hypothalamic control of the reproductive axis.In neuroendocrinology research, Kisspeptin-10 is a standard reference compound for studies of GnRH neuron activation, pituitary gonadotropin secretion dynamics (LH and FSH), and the upstream hypothalamic signaling that governs reproductive-axis maturation.
Additional research applications include metabolic-signaling studies, vascular biology, and tumor cell-biology research where kisspeptin signaling is implicated.Kisspeptin-10 is among the shorter peptides in the catalog, with correspondingly more flexibility in sizing and pricing.
Research applications
- KISS1R/GPR54 receptor pharmacology
- Hypothalamic GnRH neuron activation research
- HPG-axis reproductive-endocrine signaling
- Tumor cell-migration (metastasis) biology
- Metabolic-signaling intersections with reproductive axis
Technical profile
- Molecular formula
- C63H83N17O14
- Molecular weight
- 1302.46 g/mol
- CAS
- 388138-21-4
- Sequence
- Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH₂
For research use only. Not for human or veterinary consumption. Not intended to diagnose, treat, cure, or prevent any disease. Catalog availability restricted to verified licensed practitioners.
Kisspeptin-10 is a truncated form of the kisspeptin neuropeptide that acts on the GPR54 receptor to stimulate gonadotropin-releasing hormone (GnRH) secretion. It plays a key role in reproductive endocrinology and puberty initiation research.
