NAD+

NAD+ (nicotinamide adenine dinucleotide, oxidized form) is an endogenous dinucleotide coenzyme present in all living cells. Structurally distinct from the peptides in this catalog, NAD+ is a cornerstone reference compound in cellular-energy, redox, and aging-biology research. It participates as a substrate or cofactor in hundreds of enzymatic reactions, most notably those of the electron-transport chain, the NAD+/NADH redox couple, the sirtuin family of deacylases (SIRT1–SIRT7), PARP (poly-ADP-ribose polymerase) enzymes, and the CD38 ectoenzyme.

Age-related decline in tissue NAD+ levels has been a focus of the gerontology literature for more than two decades, and the compound has become a foundational research tool in longevity biology. Published investigations have examined NAD+ metabolism in the context of mitochondrial bioenergetics, sirtuin-mediated gene regulation, DNA-damage response signaling, and circadian rhythm biology.

NAD+ is cataloged at large milligram quantities reflecting both its low per-mg synthesis cost and the typical use volumes in cell-culture, tissue-assay, and formulation research. Supplied by Novera as a crystalline powder for in-vitro laboratory research applications only — the crystalline form is preferred over lyophilizate for stability and handling characteristics. NAD+ is a coenzyme, not a peptide; it is included in the catalog as a complementary research tool for laboratories working alongside longevity-focused peptide investigations.