Cognitive & NeuroprotectiveIn StockCognitive & Neuroprotective
Semax
Also known as: ACTH(4-10) analog, Met-Glu-His-Phe-Pro-Gly-Pro
Synthetic heptapeptide derived from ACTH(4-10); studied in BDNF/NGF expression and neuroprotective research.
Semax is a synthetic heptapeptide developed at the Russian Academy of Sciences as an analog of the ACTH(4-10) sequence, with an additional Pro-Gly-Pro C-terminal extension for enzymatic stability.
It was designed to retain the neurotropic properties of ACTH(4-10) without the corticosteroid-stimulating activity.The research literature on Semax, again largely originating from Russian research groups, examines upregulation of brain-derived neurotrophic factor (BDNF) and nerve growth factor (NGF), neuroprotective signaling in ischemic-stroke preclinical models, and effects on cognitive-performance endpoints in behavioral studies.Semax is typically supplied in larger vial sizes (10mg, 30mg) than most injectable peptides, reflecting its use pattern in both injectable and intranasal research preparations.
Research applications
- BDNF and NGF expression research
- Neuroprotective signaling in ischemic-injury models
- Cognitive-performance behavioral studies
- Anxiolytic and stress-adaptation research
- Melanocortin-pathway-derived peptide biology
Technical profile
- Net content
- 30 mg
- Molecular formula
- C39H54N10O10S
- Molecular weight
- 813.98 g/mol
- CAS
- 80714-61-0
- Sequence
- Met-Glu-His-Phe-Pro-Gly-Pro
For research use only. Not for human or veterinary consumption. Not intended to diagnose, treat, cure, or prevent any disease. Catalog availability restricted to verified licensed practitioners.
Semax is a synthetic heptapeptide derived from the N-terminal fragment of adrenocorticotropic hormone (ACTH 4-10). It enhances BDNF expression, improves cognitive function, and demonstrates neuroprotective effects against oxidative damage and ischemia.
