Cognitive & NeuroprotectiveIn StockCognitive & Neuroprotective
BDNF
Also known as: Brain-Derived Neurotrophic Factor (recombinant mature protein)
Recombinant 119-amino-acid mature neurotrophin protein; standard reference for TrkB receptor signaling research.
BDNF (brain-derived neurotrophic factor) is a member of the neurotrophin family of secreted growth factors.
The recombinant mature protein is the 119-amino-acid product of proteolytic cleavage from the proBDNF precursor, forming a non-covalent homodimer in solution.In research settings, BDNF is a standard reference compound for studies of the TrkB receptor (tyrosine kinase receptor B) and the p75 neurotrophin receptor, and for downstream signaling pathways including PI3K/AKT, MAPK/ERK, and PLCγ.
It is widely used in neuroscience cell-culture research on neuronal survival, synaptic plasticity, and neurogenesis models.As a recombinant protein (rather than a chemically synthesized peptide), BDNF is typically supplied in small (1mg) vials reflecting both production cost and typical research volumes.
Research applications
- TrkB receptor signal-transduction
- p75 neurotrophin receptor research
- Neuronal survival and neurogenesis research
- Synaptic plasticity and LTP/LTD studies
- Cell-culture neuroscience reference protein
Technical profile
- Net content
- 10 mg
- Molecular formula
- Recombinant protein — see Certificate of Analysis
- Molecular weight
- ~13.5 kDa (mature monomer)
- CAS
- 218441-99-7
- Sequence
- 119-amino-acid recombinant mature BDNF sequence
For research use only. Not for human or veterinary consumption. Not intended to diagnose, treat, cure, or prevent any disease. Catalog availability restricted to verified licensed practitioners.
Brain-Derived Neurotrophic Factor (BDNF) is a neurotrophin essential for neuronal survival, differentiation, and synaptic plasticity. It supports long-term potentiation and is studied for its roles in learning, memory, and neurodegenerative disease models.
