Longevity & Cellular HealthIn StockLongevity & Cellular Health
SS-31
Also known as: Elamipretide, Bendavia, MTP-131
Mitochondria-targeted synthetic tetrapeptide that concentrates at the inner mitochondrial membrane and interacts with cardiolipin.
SS-31 (elamipretide) is a synthetic tetrapeptide belonging to the Szeto–Schiller family of mitochondria-targeted peptides.
Its aromatic-cationic structure enables 1,000-fold concentration at the inner mitochondrial membrane without requiring a mitochondrial membrane potential — a feature that has made it valuable as a research tool in bioenergetics research.The compound was originally developed as a clinical therapeutic by Stealth BioTherapeutics and advanced through Phase 3 trials in several indications, including primary mitochondrial myopathy and heart failure.
It is referenced extensively in mitochondrial-biology, cardiolipin, and cardiovascular-research literature.Research applications focus on cardiolipin stabilization, electron-transport-chain protection, reactive-oxygen-species scavenging, and mitochondrial-membrane architecture in both cell-culture and animal-model settings.
Research applications
- Mitochondrial bioenergetics and inner-membrane biology
- Cardiolipin-stabilization research
- Reactive oxygen species (ROS) scavenging studies
- Cardiovascular and heart-failure models
- Aging-hallmarks research (mitochondrial dysfunction)
Technical profile
- Net content
- 10 mg
- Molecular formula
- C32H49N9O5
- Molecular weight
- 639.78 g/mol
- CAS
- 736992-21-5
- Sequence
- D-Arg-(2',6'-dimethyl)Tyr-Lys-Phe-NH2
For research use only. Not for human or veterinary consumption. Not intended to diagnose, treat, cure, or prevent any disease. Catalog availability restricted to verified licensed practitioners.
SS-31 (Elamipretide) is a mitochondria-targeted tetrapeptide that selectively binds cardiolipin in the inner mitochondrial membrane. It stabilizes electron transport chain function, reduces reactive oxygen species, and is studied for mitochondrial dysfunction and aging.
