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DSIP
Also known as: Delta Sleep-Inducing Peptide
Synthetic 9-amino-acid peptide originally isolated from rabbit cerebral venous blood; studied in sleep-architecture research.
DSIP (delta sleep-inducing peptide) is a synthetic 9-amino-acid peptide first isolated in 1977 by Schoenenberger and Monnier from the cerebral venous blood of rabbits that had been subjected to electrical stimulation of thalamic sleep-promoting regions.In the research literature, DSIP has been studied for effects on sleep architecture (particularly delta-wave activity), ACTH and cortisol modulation, and various neuroendocrine endpoints.
Despite more than four decades of research, its precise mechanism of action and endogenous receptor (if any) remain incompletely characterized — which has made it a subject of continuing academic interest.DSIP is cataloged as a mature, stable-priced research peptide with consistent mid-tier availability across US suppliers.
Research applications
- Sleep-architecture and delta-wave EEG research
- Neuroendocrine signaling (HPA axis modulation)
- Circadian-rhythm biology
- Opioid-withdrawal preclinical models
- Endogenous peptide-discovery research
Technical profile
- Net content
- 5 mg
- Molecular formula
- C35H48N10O15
- Molecular weight
- 848.81 g/mol
- CAS
- 62568-57-4
- Sequence
- Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu
For research use only. Not for human or veterinary consumption. Not intended to diagnose, treat, cure, or prevent any disease. Catalog availability restricted to verified licensed practitioners.
Delta Sleep-Inducing Peptide (DSIP) is a neuropeptide that promotes delta-wave sleep and modulates neuroendocrine function. Research suggests it may help regulate circadian rhythms, reduce stress-related hormones, and improve sleep architecture.
